|Statement||edited by John G. Forte, David G. Warnock, Floyd C. Rector, Jr.|
|Contributions||Forte, John G., Warnock, David G., Rector, Floyd C., American Physiological Society (1887- ). Fall Meeting|
|LC Classifications||QP88.4 .H93 1984|
|The Physical Object|
|Pagination||xxii, 479 p. :|
|Number of Pages||479|
|LC Control Number||84011935|
The epithelia of the thick ascending limb of the loop of Henle (see Fig. C) have numerous mitochondria and apical microvilli, consistent with the metabolically coupled reabsorption of sodium, chloride, potassium, calcium, bicarbonate, and magnesium. The thick ascending limb of the loop of Henle also secretes hydrogen ion. Figure and Table summarize renal epithelial transport. The proximal tubule epithelia (see Fig. A) have extensive apical microvilli, enhancing the surface area available for the reabsorption of electrolytes, water, glucose, and amino acids. The proximal tubule also secretes hydrogen ions, organic acids, and organic bases. With few exceptions, all the internal and external body surfaces of animals, such as the skin, stomach, and intestines, are covered with a layer of epithelial cells called an epithelium (see Figure ). Many epithelial cells transport ions or small molecules from one side to the other of the epithelium. Those lining the stomach, for instance, secrete hydrochloric acid into the stomach lumen Cited by: 2. Ion transport accomplished by the pulmonary epithelial cells is imperative for proper lung function. Although the basic mechanisms of transepithelial ion transport are defined, it is obvious that a detailed knowledge concerning the underlying processes and the interaction of the different ion transporting proteins in particular is poorly Cited by:
Three epithelia are examined as a means of exploring molecular mechanisms of fluid and ion transport. The Malpighian tubules of insects are the site of urine production and can transport a variety of ions and organic compounds. The energy for these processes is generated by a hydrogen ATPase at the apical membrane while a Na+/K+ ATPase energizes the basal surface. Hydrogen ion, strictly, the nucleus of a hydrogen atom separated from its accompanying electron. The hydrogen nucleus is made up of a particle carrying a unit of positive electric charge, called a proton. In common usage, the term hydrogen ion is used to refer to the hydrogen ion present in water solutions. Harvey B.J., Urbach V. () Regulation of Ion and Water Transport by Hydrogen Ions in High Resistance Epithelia. In: Heisler N. (eds) Mechanisms of Systemic Regulation: Acid—Base Regulation, Ion-Transfer and Metabolism. Advances in Comparative and Environmental Physiology, vol Springer, Berlin, HeidelbergCited by: 2. A broad spectrum of methods has been applied to many epithelia in a variety of species. For the individual epithelia transport schemes have been proposed, and, at this point I think it is appropriate to take a pause and search for elements common to several epithelia.
Defective epithelia ion transport in cystic fibrosis Article Literature Review (PDF Available) in Clinical Chemistry 35(5) June with 48 Reads How we measure 'reads'Author: Paul Quinton. A hydrogen ion is created when a hydrogen atom loses or gains an electron.A positively charged hydrogen ion (or proton) can readily combine with other particles and therefore is only seen isolated when it is in a gaseous state or a nearly particle-free space. Due to its extremely high charge density of approximately 2×10 10 times that of a sodium ion, the bare hydrogen ion cannot exist freely. Cell Biology of H+ Transport in Epithelia. the existence of a linked sodium-for-hydrogen ion exchange mechanism at the luminal border of the tubule cells, but there are other possibilities. Ensembl ENSG ENSMUSG UniProt Q9UBY0 n/a RefSeq (mRNA) NM_ NM_ RefSeq (protein) NP_ n/a Location (UCSC) Chr 2: – Mb Chr 1: – Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sodium–hydrogen exchanger 2 is a protein that in humans is encoded by the SLC9A2 gene. See also Aliases: SLC9A2, NHE2, solute carrier family 9 member A2.